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15 companies that will change the world

These game-changing startups are likely to upend existing industries - and spawn new entrepreneurial opportunities.

Blinkx
Chandratillake wants Blinkx to become the Google of Web video by placing contextual ads inside clips.
Blinkx
CEO: Suranga Chandratillake
Disruption: Web video search and ad insertion
Disrupted: Search engines and the TV ad business

The fastest growing segment of Internet advertising is video, and Blinkx's video search engine aims to capitalize on the trend. Blinkx indexes more than 14 million hours of video available on the Web, using software that turns speech into text and counts how many times a given word pops up in a video. That allows the company to target ads to video content, putting it a step ahead of big challengers like Google and Yahoo.

Blinkx

Raydiance

Expensr

Zipcar

MFG.com

Virgin Charter

PatientsLikeMe

Bloom Energy

Vanu

Zink

A123 Systems

Renewable Energy Group

Desktop Factory

Cree

One laptop per child
The New Disruptors video series Editor-at-Large Erick Schonfeld discovers startups with the potential to overturn existing industries or open up entirely new markets. (more)
Tomorrow's light With companies developing innovative ways to fight global warming, Cree founder John Edmond describes how LED lights are poised to change the way we see things. (more) video