Pharmaceuticals News
January 16, 2016

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updated 9:50pm EST

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January 16, 2016

Researchers Develop Novel Cell Line for Screening of Brain Drugs

Jan. 14, 2016 — A new cell line has been developed, which may be used to investigate new drugs and help predict whether they are able to enter the brain. This research will afford scientists in both academia and the ... read more

Even After Anti-Androgen Therapy, Docetaxel Remains Useful in Prostate Cancer

Jan. 11, 2016 — 40 percent of patients with castration-resistant metastatic prostate cancer (mCRPC) treated with docetaxel following abiraterone had at least 50 percent reduction in prostate specific antigen (PSA), ... read more

Jan. 8, 2016 — A small molecule drug combined with chemotherapy may deliver a synergistic benefit for colorectal cancer patients, new research suggests. has demonstrated the efficiency of a small molecule drug, ... read more

Current Malaria Treatment Fails in Cambodia Due to Drug-Resistant Parasites

Jan. 8, 2016 — New findings confirm dihydroartemisinin-piperaquine, the first-line treatment for Plasmodium falciparum malaria infection in Cambodia, has failed in certain provinces due to parasite resistance to ... read more

New Role of Protein Kinases in Embryo Development and Cancer

Jan. 7, 2016 — A group of protein kinases have been found to play an important role in embryo development and may even be a potential cancer drug target, a research team ... read more

New Drug May Overcome Treatment Resistance in a High-Risk Children's Cancer

Jan. 6, 2016 — Pediatric oncologists have reported their latest results in devising new treatments for stubbornly deadly forms of the childhood cancer neuroblastoma. The 'unparalleled' strength of an ALK ... read more

Multiple Myeloma Study Pivotal for FDA Approval of Daratumumab

Jan. 6, 2016 — Multiple myeloma testing of daratumumab (trade name Darzalex) have received accelerated approval from the US FDA in November ... read more

Cancer Drug Shows Promise for Treating Duchenne Muscular Dystrophy

Jan. 6, 2016 — A drug commonly used to treat leukemia is showing potential as a treatment that could slow the progression of the muscle-wasting condition, Duchenne muscular ... read more

Cannabis-Based Drug Reduces Seizures in Children With Treatment-Resistant Epilepsy

Jan. 5, 2016 — Children and young adults with severe forms of epilepsy that does not respond to standard antiepileptic drugs have fewer seizures when treated with purified cannabinoid, according to a multi-center ... read more

Inside the Hepatitis C Virus Is a Promising Antiviral

Jan. 5, 2016 — A peptide derived from the hepatitis C virus (HCV) kills a broad range of viruses while leaving host cells unharmed by discriminating between the molecular make-up of their membranes, reveals a ... read more

Use of Anticholinergic Drugs Does Not Increase Risk for Dementia in Parkinson's Disease Patients

Jan. 5, 2016 — Recent evidence has shown a greater risk of dementia, in particular Alzheimer's disease (AD), in individuals using anticholinergic medications regularly. These drugs are widely used by older ... read more

Experts Question Automatic Osteoporosis Drug Holidays

Jan. 4, 2016 — A new editorial urges physicians to individualize treatment decisions based on their patients' fracture risk, rather than automatically interrupting or stopping bisphosphonate therapy after five ... read more

U.S. Emergency Departments Face Serious Drug Shortages

Jan. 4, 2016 — A new study reveals that drug shortages affecting emergency care have skyrocketed in the United States in recent years. While the prevalence of such shortages fell from 2002 to 2007; the number of ... read more

Anti-Inflammatory Drug and Gut Bacteria Have a Dynamic Interplay

Jan. 4, 2016 — An NSAID changed the composition and diversity of gut microbes, which in turn shaped how the drug is broken down and ultimately, cut its effectiveness, researchers report at the conclusion of an ... read more

Biggest Database for Cancer Drug Discovery Goes 3-D

Jan. 4, 2016 — The world's largest database for cancer drug discovery has been revolutionized by adding 3-D structures of faulty proteins and maps of cancer's communication networks, according to a new ... read more

Three Hits to Fight Lung Cancer

Jan. 4, 2016 — Cancers with KRAS-related gene mutations might benefit from a triple therapy with two experimental drugs plus radiation therapy, a new study in mice has ... read more

Saffron-Based Crocin Prevents Liver Cancer: Preclinical Studies and Beyond

Jan. 4, 2016 — Liver cancer remains among the leading causes of cancer-related death worldwide. Now new research unravels mechanisms by which saffron-based 'crocin' protects against liver ... read more

Dec. 29, 2015 — Formulating drugs as liquid salts may provide a safe and efficient strategy for topical delivery of drugs that cause skin toxicity, say ... read more

Mapping Cancer's 'Social Networks' Opens New Approaches to Treatment

Dec. 23, 2015 — A computer model has been designed that applies techniques used to analyze social networks to identify new ways of treating cancer, according to a new ... read more

Personalizing Cancer Therapies May Combat Resistance to Targeted Therapy Drugs

Dec. 23, 2015 — American physicians report the case of a patients whose lung cancer was re-sensitized to crizotinib, a first-generation targeted therapy drug, by a mutation conferring resistance to a more selective, ... read more

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