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Vioxx News

September 6, 2016

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Scientists Show Commonly Prescribed Painkiller Slows Cancer Growth

May 25, 2016 — Scientists have found that one of the most widely prescribed pain and anti-inflammation drugs slows the growth rate of a specific kind of cancer in animal models and suggests ... read more

Study Quells Concerns About NAID Safety

Aug. 31, 2015 — In older patients with arthritis and no history of cardiovascular disease, chronic use of any non-steroidal anti-inflammatory drug appears safe from a cardiovascular and gastrointestinal stand-point, ... read more

Biomarker Discovery Sheds New Light on Heart Attack Risk of Arthritis Drugs

Dec. 10, 2014 — A class of drug for treating arthritis - all but shelved over fears about side effects - may be given a new lease of life, following the discovery of a possible way to identify which patients should ... read more

More Evidence Arthritis/pain Relieving Drugs May Contribute to Stroke Death

Nov. 5, 2014 — Commonly prescribed, older drugs for arthritis and pain may increase the risk of death from stroke, according to a study. "Our study supports stepping up efforts to make sure people with a higher ... read more

Common Painkillers Combined With Other Drugs May Cause High Risk of GI Bleeding

Oct. 2, 2014 — Nonsteroidal anti-inflammatory drugs -- such as ibuprofen and aspirin -- increase one's risk of upper gastrointestinal bleeding. When taken in ... read more

Safer Alternatives to Nonsteroidal Antinflamatory Pain Killers

Apr. 21, 2014 — Building on previous work that showed that deleting an enzyme in the COX-2 pathway in a mouse model of heart disease slowed the development of atherosclerosis, researchers ... read more

Popular Pain Relievers May Reduce Risk of Bladder Cancer

Nov. 7, 2012 — Researchers have found that duration of ibuprofen use was associated with a reduced risk of bladder cancer in patients in northern New England, which has a high mortality rate of this ... read more

NSAIDs and Cardiovascular Risk Explained

May 2, 2012 — After nearly 13 years of study and intense debate, a pair of new articles have confirmed exactly how a once-popular class of anti-inflammatory drugs leads to cardiovascular risk for people taking ... read more

Study of COX-2 Inhibitors Could Lead to New Class of Stroke Drugs

Oct. 3, 2011 — A new study in mice points toward potential new therapies for stroke, a leading cause of death and foremost single cause of severe neurological disability. The study also may reveal why a ... read more

Common Painkillers Linked to Increased Risk of Heart Problems

Jan. 11, 2011 — Commonly used painkillers for treating inflammation can increase the risk of heart attacks and strokes, according to an analysis of the ... read more

Using Some Heartburn Drugs May Increase Your Risk Of Kidney Problems

Heart Drugs May Help Breast Cancer Patients

Generics Eat Into Pfizer's Sales

Yogurt Reduces Diabetes Risk: Study

Separating a Cancer Prevention Drug from Heart Disease Risk

Sep. 13, 2011 — Celecoxib reduces the risk of developing precancerous colon polyps, at the cost of increased heart disease risk. By looking closely at how celecoxib acts in the cell, it may be possible to get the ... read more

Why Drugs Increase Risk of Heart Attacks and Strokes: Analysis Highlights Cardiovascular Risk of Fluid Retention

Feb. 22, 2011 — New research shows that medications which have raised safety concerns over heart attack and stroke risks may not have gotten approval from the US Food and Drug Administration if the cardiovascular ... read more

Widely Used Arthritis Pill Protects Against Skin Cancer, Study Suggests

Dec. 2, 2010 — A widely used arthritis drug reduces the incidence of non-melanoma skin cancers -- the most common cancers in humans -- according to a new study. The COX-2 inhibitor celecoxib (Celebrex), which is ... read more

Celecoxib (Celebrex) May Be Effective in Preventing Non-Melanoma Skin Cancers

Nov. 29, 2010 — Celecoxib (also known by its brand name Celebrex) may help prevent non-melanoma skin cancers in patients with extensive actinic keratosis, which is often a precursor to these cancers, according to a ... read more

Link Between Arthritis Pain Reliever and Cardiovascular Events Discovered

Sep. 13, 2010 — Researchers have discovered a novel mechanism as to why the long-term, high-dosage use of the well-known arthritis pain medication, Vioxx, led to heart attacks and strokes. Their groundbreaking ... read more

Can Celebrex Prevent Cancer-Causing Colon Polyps?

May 13, 2010 — Researchers are testing whether celecoxib, known by its brand name Celebrex, can help prevent the growth of precancerous polyps that form in the colon, rectum and small intestine of children with an ... read more

Painkiller Undermines Aspirin's Anti-Clotting Action

Dec. 14, 2009 — Millions of Americans take Celebrex for arthritis or other pain. Many, if they are middle-aged or older, also take a low-dose aspirin tablet daily to reduce the risk of heart attack and stroke. Yet ... read more

Vioxx Trial Data Shows Early Cardiovascular Risk

Nov. 23, 2009 — Evidence of cardiovascular risks associated with taking Vioxx, the popular, nonsteroidal anti-inflammatory drug (rofecoxib), could have been identified nearly four years before its manufacturer, ... read more

Discovery In Colon Cancer Prevention

May 18, 2009 — A new study finds that individuals who have low expression of the "Celebrex gene," 15-PGDH, are actually resistant to Celebrex treatment when used to prevent colon ... read more

Potential Lung Disease Biomarkers Yield Clues To COX-2 Inhibitor Side Effects

Apr. 29, 2009 — In searching for a simple way to identify individuals with smoking-related lung injury, scientists at have stumbled upon a potential explanation for why the class of pain-relievers known as COX-2 ... read more

Licorice Compound Offers New Cancer Prevention Strategy

Mar. 24, 2009 — A chemical component of licorice may offer a new approach to preventing colorectal cancer without the adverse side effects of other preventive therapies, researchers ... read more

Prostaglandin Receptor Key To Atherosclerosis Development

Dec. 15, 2008 — Atherosclerosis -- a disease that includes the buildup of fatty, cholesterol-laden lumps of cells inside the artery wall -- is the underlying cause of heart attacks and strokes. Researchers have now ... read more

Prostate Cancer Can Be Halted With Anti-Inflammatory And Statin Used In Tandem, Study Suggests

Apr. 14, 2008 — Researchers have shown that administering a combination of the widely used drugs Celebrex (celecoxib, a nonsteroidal anti-inflammatory drug) and Lipitor (atorvastatin, a cholesterol lowering drug) ... read more

Potential New Drug Targets Against Hormone-Dependent Breast Cancer Identified

Feb. 28, 2008 — The identification of two cellular receptors that likely contribute to the genesis of hormone-dependent breast cancer points the way to new, highly targeted therapies against the disease. The finding ... read more

Popular Arthritis Drug May Disrupt Heart Rhythm, New Research Finds

Jan. 24, 2008 — Celebrex, a popular arthritis drug that blocks pain by inhibiting an enzyme known as COX-2, has been shown in laboratory studies to induce arrhythmia, or irregular beating of the heart, via a novel ... read more

Celecoxib Can Adversely Affect Heart Rhythm, Study Suggests

Jan. 14, 2008 — COX-2 inhibitors like Celecoxib have come under scrutiny lately due to adverse cardiovascular side-effects stemming from COX-2 reduction. In both fruit fly and rat models, researchers reveal another ... read more

Vioxx Side-Effects: Possible Explanation

Aug. 27, 2007 — Vioxx and related pain medications were taken off the market in 2004 because they caused dangerous heart problems in some people. Scientists may now have figured out how these drugs trigger these ... read more

Celecoxib Helps Prevent Restenosis And Appears Safe

Aug. 18, 2007 — Adjunctive use of the COX-2 inhibitor celcoxib after stent implantation in patients with coronary artery disease appears safe and can reduce the need for revascularisation of the target lesion, ... read more

Researcher Lays Out Benefits Of Aspirin To Prevent Colon Cancer

May 23, 2007 — A colon cancer researcher has laid out in a recent article how he thinks medical science should employ aspirin and new aspirin-like drugs for use in preventing colon cancer in certain high-risk ... read more

Combining NSAIDs With Chemotherapy, Radiation May Improve Cancer Treatment

May 17, 2007 — Certain nonsteroidal anti-inflammatory drugs may be better suited to treating cancer, in combination with standard therapies, rather than preventing it, according to new ... read more

Tuesday, September 13, 2011