Personalized Medicine News

September 5, 2016

Reprogramming Cell's Identity With Gene Editing

Complex Grammar of the Genomic Language

High-Fat Diet: Profound Effect On Inuit

Human Blood Turned Into Brain Cells

Latest Headlines

updated 12:33pm EDT

Novel Culprit for Type 2 Diabetes Gene at Well-Established Genomic Location

Aug. 31, 2016 — Gene researchers have used sophisticated scientific tools to reveal a new gene for type 2 diabetes at a well-established genomic location. Because ... read more

Breast Cancer Researchers Look Beyond Genes to Identify More Drivers of Disease Development

Aug. 29, 2016 — Breast cancer researchers have discovered that mutations found outside of genes that accumulate in estrogen receptor ... read more

Single Gene Mutation Causes Severely Debilitating Disease of Brain Blood Vessels

Aug. 29, 2016 — The cause of a disease that targets blood vessels in the brain -- leading to multiple debilitating symptoms and, often, to early death -- has been ... read more

Asthma Risk Increases When Child Had Bronchiolitis

Aug. 24, 2016 — Asthma risk increased 17 times when children who had bronchiolitis in the first two years of life also had a common variation of the Plasminogen activator inhibitor-1 gene, new research ... read more

Heart Muscle Made from Stem Cells Aid Precision Cardiovascular Medicine, Study Shows

Aug. 18, 2016 — Heart muscle cells made from induced pluripotent stem cells faithfully mirror the expression patterns of key genes in the donor's native heart ... read more

Music Demonstrated to Alleviate Cancer Patients' Symptoms

Aug. 17, 2016 — A review looking at studies on the effect music interventions have on the treatment of cancer patients found treatment benefits for anxiety, pain, fatigue and overall quality of ... read more

Gene Variant Explains Differences in Diabetes Drug Response

Aug. 16, 2016 — A large international study of metformin, the world’s most commonly used type 2 diabetes drug, reveals genetic differences among patients that may explain why some respond much better to the drug ... read more

Researchers Pinpoint Key Regulatory Role of Noncoding Genes in Prostate Cancer Development

Aug. 15, 2016 — Prostate cancer researchers studying genetic variations have pinpointed 45 genes associated with disease development and progression, a new report ... read more

Analysis of Metastatic Prostate Cancers Suggests Treatment Options

Aug. 10, 2016 — A new study maps out abnormal signaling pathways in prostate cancer cells and provides computational approaches to identify individualized targets ... read more

New Study Shows Breast Tumors Evolve in Response to Hormone Therapy

Aug. 9, 2016 — A new analysis of breast tumors, before and after hormone-reduction therapy, reveals the extreme genetic complexity of these tumors and the variety of responses that are ... read more

Ray of Light for Prostate Cancer Treatment

Cancer Patients Suffer Through Futile Treatments

New Findings Could Boost Type 1 Diabetes Treatment and Prevention

DNA Blood Test Predicts Suspects' Age

Genetic Diversity of Enzymes Alters Metabolic Individuality

Sep. 1, 2016 — New research about genetic diversity and metabolome has been released by scientists. These findings are based on the analysis of blood samples from 512 healthy ... read more

System Helps Protect Privacy in Genomic Databases

Aug. 9, 2016 — In a new study, researchers describe a new system that permits database queries for genome-wide association studies but reduces the chances of privacy compromises to almost ... read more

Research Reveals Patient Can Have More Than One Breast Cancer, Points at Treatments

Aug. 9, 2016 — Breast cancer tumors are complex and dynamic. They comprise a population of continuously dividing cells that carry different genetic mutations. New research reveals that treating human ... read more

Sex Hormones Skew Outcomes in Clinical Trials -- Here's How

Aug. 9, 2016 — Clinical research often excludes females from their trials under the assumption that 'one size fits all,' that a painkiller or antidepressant will be equally effective in subjects of either ... read more

New Testing Method Developed for Genetic Mutation That Causes Pulmonary Hypertension

Aug. 9, 2016 — The new testing method is a significant improvement for patients because it utilizes a simple blood sample, eliminating the need for a much more invasive lung biopsy that was previously required to ... read more

Highly Curative Hep C Treatment Safe, Effective for Drug Users

Aug. 9, 2016 — Hep C patients being treated for opioid addiction achieved high rates of sustained virologic response after 12 weeks of therapy with elbasvir-grazoprevir compared to those taking placebo for 12 weeks ... read more

Complex Genetic Secrets of Cancer Risk Uncovered

Aug. 4, 2016 — In a landmark multi-country study, researchers have transformed our understanding of the genes that affect our risk of cancer. The researchers uncovered numerous new genetic risk factors for the bone ... read more

African-American Men Negatively Impacted by Hormone Therapy for Treatment of Prostate Cancer

Aug. 4, 2016 — In a retrospective study analyzing patients' medical records, researchers found that patients' race significantly affected their longevity by increasing the likelihood of death after ... read more

Analysis of Metastatic Prostate Cancers Suggests Treatment Options

Aug. 4, 2016 — Cancer researchers have applied a comprehensive set of analytical tools to lethal cases of metastatic prostate cancer, yielding a detailed map of the complex networks of interactions among genes and ... read more

Pancreatic Cancer Resists Personalized Medicine: What Researchers Are Doing to Fight Back

Aug. 4, 2016 — Researchers are taking a new, patient-directed approach to treating pancreatic cancer. Rather than relying on conventional cell lines that have defined effective drug targets for other types of ... read more

Largest-Ever Whole Genome Autism Study Yields Clues on How Autism-Linked Gene Changes Arise

Aug. 4, 2016 — A new study expands understanding of autism's complex causes and may hold clues for the future development of targeted treatments. The report is the largest-ever whole genome study of autism, ... read more

New Biochip-Based Blood Test Detects Elevated Risk for Alzheimer’s Disease

Aug. 3, 2016 — Researchers today unveiled results from a new blood test to help identify which patients are at an elevated risk of Alzheimer’s disease. The findings showed that the biochip test, which allows ... read more

First Next-Generation Sequencing Test for HIV Drug Resistance Could Help Combat AIDS Worldwide

Aug. 3, 2016 — New research demonstrates that a first-of-its-kind next-generation sequencing test can detect HIV drug resistance mutations that conventional tests fail to identify. This test could play a critical ... read more

Stem Cells May Speed Up Screening of Drugs for Rare Cancers

Aug. 2, 2016 — A new system has been developed that uses transformed human stem cells to speed up screening of existing drugs that might work against rare brain and other ... read more

Novel Study Method Identifies 15 Genomic Regions Associated With Depression

Aug. 1, 2016 — A genomic study using a novel method of enrolling participants has identified for the first time 15 regions of the genome that appear to be associated with depression in individuals of European ... read more

FAMIN or Feast? Newly Discovered Mechanism Influences How Immune Cells 'Eat' Invaders

Aug. 1, 2016 — A new mechanism that affects how our immune cells perform -- and hence their ability to prevent disease -- has been discovered by an international team of ... read more

Virtual Brain Helps Decrypt Epilepsy

July 29, 2016 — A virtual brain has been created that can reconstitute the brain of a person affected by epilepsy for the first time. From this work we understand better how the disease works and can also better ... read more

Sampling Method Used for New Breast Cancer Tests May Lead to Underestimation of Risk

July 28, 2016 — Not only is breast cancer more than one disease, but a single breast cancer tumor can vary within itself, giving the potential for very different patient treatment plans depending on the tumor sample ... read more

Updated Testing Guidelines Make More Women Eligible for Herceptin, Yet Benefit Uncertain

July 27, 2016 — Changes to HER2 testing guidelines for breast cancer in 2013 significantly increased the number of patients who test HER2-positive, according to a new study. Cancers that have an excess of HER2 ... read more

Gene Therapy in a Droplet Could Treat Eye Diseases, Prevent Blindness

July 27, 2016 — Eye diseases such as diabetic retinopathy and age-related macular degeneration are among the leading causes of irreversible vision loss and blindness worldwide. Currently, gene therapy can be ... read more

Thursday, September 1, 2016