Apr. 15, 2016 — There may be a new way to change the damaging course of Huntington disease, researchers report. They have shown that reducing the aberrant accumulation of a particular form of the mutant Huntingtin ...
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Mar. 7, 2016 — Scientists have parsed the role of the Huntington's disease gene in an area of the songbird's brain responsible for complex, sequential movements. These findings not only give a clearer ...
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Mar. 3, 2016 — Protein aggregates are deemed to be one reason for the death of nerve cells in disorders such as Alzheimer's or Huntington's disease. Synthesis of faulty protein chains leads to the ...
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Feb. 3, 2016 — The core of the protein clumps found in the brains of people with Huntington's disease have a distinctive structure, a finding that could shed light on the molecular mechanisms underlying the ...
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Dec. 7, 2015 — Currently, there is no treatment to halt the progression of Huntington's disease (HD), a fatal genetic disorder that slowly robs sufferers of their physical and mental abilities. Now, ...
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Nov. 19, 2015 — A new discovery about Huntington's disease has been made by researchers, showing that the gene that causes the fatal disorder makes an unexpected 'cocktail' of mutant proteins that ...
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Oct. 13, 2015 — A well-established anti-epileptic drug could also be used as a treatment for neurodegenerative diseases, report scientists investigating the ...
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Aug. 11, 2015 — Variable polyglutamine repeats in the DNA tune the function of the protein in which they reside, scientists report. To date, these repeats were known only to cause severe neurodegenerative diseases ...
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Aug. 7, 2015 — Scientists searched the chromosomes of more than 4,000 Huntington's disease patients and found that DNA repair genes may determine when the neurological symptoms begin. The results may provide a ...
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Aug. 7, 2015 — A new test allows physicians to measure the effects of gene silencing therapy in Huntington's disease and will support the first human clinical trial of a drug that targets the genetic cause of ...
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July 30, 2015 — A study that took a novel approach to investigating factors affecting the emergence of symptoms of Huntington's disease has identified at least two genome sites that house variants that can ...
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July 13, 2015 — Fingolimod, a drug used to treat multiple sclerosis, restores hippocampal synaptic plasticity and improves memory function. This is the main conclusion of a study in a mouse model of Huntington ...
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June 30, 2015 — A type of genetic material called “microRNA” plays surprisingly different roles in the formation of memory in animal models, researchers have found. In some cases, these RNAs increase memory, ...
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May 12, 2015 — A preclinical, large animal model of Huntington's disease has been developed for assessing new therapeutics, which could ultimately provide better treatment options, possibly including altering ...
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May 5, 2015 — A gene variant that influences whether Huntington’s disease breaks out earlier or later than expected has been identified by researchers. The findings can contribute to improved diagnosis and ...
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May 4, 2015 — A closer look at the DNA around the Huntington's disease gene offers researchers a new understanding of how the gene is controlled and how this affects the disease. These findings set the stage ...
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Apr. 24, 2015 — While seeking targets to attack Huntington's disease, an incurable inherited neurodegenerative disorder, neurobiologists have found what they were looking for. Using a filtering strategy ...
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Apr. 23, 2015 — Huntington's disease is a neurodegenerative disorder characterized by huntingtin protein aggregates in a patient's brain, but how these aggregates form is not well understood. In a new ...
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Apr. 16, 2015 — Significant vascular changes in the brains of people with Huntington's disease have been identified by researchers. This breakthrough will have significant implications for our understanding of ...
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Apr. 6, 2015 — A new test has been able to measure for the first time the build-up of a harmful mutant protein in the nervous system of patients during the progression of Huntington's disease (HD). HD is a ...
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